Targeting and Beyond: New Roles for Old Signal Sequences.
Hedge BS
Molecular Cell (2002)
Category: protein transport ¤ Added: Oct 30, 2002 ¤ Rating: ◊◊
Signal sequences, once considered degenerate hy- drophobic elements whose sole task is to target pro- teins to the secretory pathway, are increasingly being recognized as playing roles beyond targeting. Recent work is beginning to shed light on some of the ways the cell decodes and exploits additional functions encoded within signal sequences.