Endocytosis: Driving Membranes around the Bend.
Hurley JH, Wendland B
Cell (2002)
Category: endocytosis ¤ Added: Oct 22, 2002 ¤ Rating: ◊◊
When a nascent vesicle buds, the membrane must curve. Several mechanisms have been proposed for curvature creation or stabilization. Structural analysis of the ENTH domain of the endocytic protein epsin has suggested a new mechanism, in which the ENTH domain pushes its way into membranes, thus bending them into shape.