|Gene Expression During the Life Cycle of Drosophila melanogaster.|
Arbeitman MN, Furlong EEM, Imam F, Johnson E, Null BH, Baker BS, Krasnow MA, Scott MP, Davis RW, White KP
Category: genomics ¤ Added: Sep 27, 2002 ¤ Rating: ◊◊
Molecular genetic studies of Drosophila melanogaster have led to profound advances in understanding the regulation of development. Here we report gene expression patterns for nearly one-third of all Drosophila genes during a complete time course of development. Mutations that eliminate eye or germline tissue were used to further analyze tissue-speciﬁc gene expression programs. These studies deﬁne major characteristics of the transcriptional programs that underlie the life cycle, compare development in males and females, and show that large-scale gene expression data collected from whole animals can be used to identify genes expressed in particular tissues and organs or genes involved in speciﬁc biological and biochemical processes.