|DNA Sliding Clamps: Just the Right Twist to Load onto DNA.|
Barsky D, Venclovas C
Current Biology (2005)
Category: DNA replication ¤ Added: Jan 21, 2006 ¤ Rating: ◊◊
Two recent papers illuminate a key step in DNA sliding clamp loading: one reveals the structure of the PCNA clamp wrapped around DNA - still open from being loaded - while the other finds that the clamp may assist this process by forming a right-handed helix upon opening.