How membrane proteins travel across the mitochondrial intermembrane space.
Koehler CM, Merchant S, Schatz G
Trends in Biochemical Sciences (1999)
Category: protein transport ¤ Added: Aug 16, 2004 ¤ Rating: ◊◊
A newly discovered family of small proteins in the yeast mitochondrial intermembrane space mediates import of hydrophobic proteins from the cytoplasm into the inner membrane. Loss of one of these chaperone-like proteins from human mitochondria results in a disease that causes deafness, muscle weakness and blindness.
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