Efg1, a morphogenetic regulator in Candida albicans, is a sequence-specific DNA binding protein.
Leng P, Lee PR, Wu H, Brown AJ
Journal of Bacteriology (2001)
Category: dimorphism ¤ Added: Jan 16, 2004 ¤ Rating: ◊◊
Efg1 is essential for hyphal development in the human pathogen Candida albicans under most conditions. Efg1 is related to basic helix-loop-helix regulators, and therefore most workers presume that Efg1 is a transcription factor. Here we confirm that Efg1 is a DNA binding protein that can interact specifically with the E box.