Untimely ends and new beginnings in mouse cloning (Commentary).
Perry AC, Wakayama T
Nature Genetics (2002)
Category: animal cloning ¤ Added: Apr 04, 2002 ¤ Rating: ◊◊
A new study shows that the majority of mice cloned from somatic cells die prematurely. Of the six dead clones analyzed, four exhibited extensive necrosis of the liver, two had tumors and all had pneumonia, suggestive of immune impairment. These latest cloning-associated phenotypes will facilitate a better understanding of the mechanisms underlying nuclear-transfer cloning in mammals.