Searching for nuclear-mitochondrial genes.
Chinnery PF
Trends in Genetics (2003)
Category: mitochondria-biogenesis ¤ Added: Mar 26, 2003 ¤ Rating: ◊◊
Recently, a novel strategy has been developed to identify yeast genes that are important for mitochondrial respiratory chain function. This approach found a large number of genes that were not previously thought to be involved, providing new candidate disease genes for mitochondrial disorders. These genes could cast light on the intricate relationship between genotype and phenotype in a wide range of inherited human diseases.