|TRAPping enhancer function.|
Bulger M, Groudine M
Nature Genetics (2002)
Category: chromatin structure ¤ Added: Dec 19, 2002 ¤ Rating: ◊◊
Enhancer elements act from distal regions to mediate the transcription of genes. A novel combination of FISH and ChIP techniques may provide new insight into the mechanism by which enhancer elements exert their control. Application of the technique to the Hbb (encoding â-globin) locus control region (LCR) suggests that elements of the LCR may be in close proximity to the transcribed â-globin genes.