The Poly(A) Tail of mRNAs: Bodyguard in Eukaryotes, Scavenger in Bacteria.
Dreyfus M, Regnier P
Cell (2002)
Category: gene expression ¤ Added: Dec 03, 2002 ¤ Rating: ◊◊
In eukaryotes, poly(A) tails usually act as stabilizers of intact mRNAs, whereas in E. coli they serve to accel- erate the destruction of fragments. The mechanisms underlying these contrasting effects of the same RNA modification are discussed.