Display Order by Show
Library » category: topoisomerase
Items 31 - 40 of 54.
DNA Disentangling by Type-2 Topoisomerases.
Buck GR, Zechiedrich EL
Journal of Molecular Biology (2004)
Category: DNA replication, topoisomerase ¤ Added: Aug 27th, 2004 ¤ Rating: ◊◊
Conserved themes but novel activities in recombinases and topoisomerases.
Sherratt DJ, Wigley DB
Cell (1998)
Category: DNA replication, mitochondrial DNA, telomere resolvase or protelomerase, topoisomerase ¤ Added: Aug 18th, 2004 ¤ Rating: ◊◊
A mutation in yeast TOP2 homologous to a quinolone-resistant mutation in bacteria. Mutation of the amino acid homologous to Ser83 of Escherichia coli gyrA alters sensitivity to eukaryotic topoisomerase inhibitors.
Hsiung Y, Elsea SH, Osheroff N, Nitiss JL
Journal of Biological Chemistry (1995)
Category: topoisomerase ¤ Added: Jul 16th, 2004 ¤ Rating: ◊◊
Increased drug affinity as the mechanistic basis for drug hypersensitivity of a mutant type II topoisomerase.
Froelich-Ammon SJ, Burden DA, Patchan MW, Elsea SH, Thompson RB, Osheroff N
Journal of Biological Chemistry (1995)
Category: topoisomerase ¤ Added: Jul 16th, 2004 ¤ Rating: ◊◊
A yeast type II topoisomerase selected for resistance to quinolones. Mutation of histidine 1012 to tyrosine confers resistance to nonintercalative drugs but hypersensitivity to ellipticine.
Elsea SH, Hsiung Y, Nitiss JL, Osheroff N
Journal of Biological Chemistry (1995)
Category: topoisomerase ¤ Added: Jul 16th, 2004 ¤ Rating: ◊◊
Identification of yeast DNA topoisomerase II mutants resistant to the antitumor drug doxorubicin: implications for the mechanisms of doxorubicin action and cytotoxicity.
Patel S, Sprung AU, Keller BA, Heaton VJ, Fisher LM
Molecular Pharmacology (1997)
Category: topoisomerase ¤ Added: Jul 16th, 2004 ¤ Rating: ◊◊
Arabidopsis thaliana DNA gyrase is targeted to chloroplasts and mitochondria.
Wall MK, Mitchenall LA, Maxwell A
Proceedings of National Academy of Sciences USA (2004)
Category: topoisomerase ¤ Added: Jul 8th, 2004 ¤ Rating: ◊◊
Quantitative structure-antitumor activity relationships of camptothecin analogues: cluster analysis and genetic algorithm-based studies.
Fan Y, Shi LM, Kohn KW, Pommier Y, Weinstein JN
Journal of Medical Chemistry (2001)
Category: DNA replication, topoisomerase ¤ Added: Jun 23rd, 2004 ¤ Rating: ◊
Topoisomerase function during replication-independent chromatin assembly in yeast.
Garinther WI, Schultz MC
Molecular and Cellular Biology (1997)
Category: topoisomerase ¤ Added: Nov 7th, 2003 ¤ Rating: ◊◊
Yeast as a model organism for studying the actions of DNA topoisomerase-targeted drugs.
Reid RJ, Benedetti P, Bjornsti MA
Biochemica et Biophysica Acta (1998)
Category: topoisomerase ¤ Added: Oct 30th, 2003 ¤ Rating: ◊