|Mitochondrial iron detoxification is a primary function of frataxin that limits oxidative damage and preserves cell longevity
Gakh O, Park S, Liu G, Macomber L, Imlay JA, Ferreira GC, Isaya G
Human Molecular Genetics (2006)
Category: aging, iron, iron-sulfur clusters, mitochondrial diseases ¤ Added: Jun 15th, 2006 ¤
|Frataxin Acts as an Iron Chaperone Protein to Modulate Mitochondrial Aconitase Activity.
Bulteau A-L, ONeill HA, Kennedy MC, Ikeda-Saito M, Isaya G, Szweda LI
Category: iron, mitochondria-biogenesis ¤ Added: Jul 12th, 2004 ¤
|The ferroxidase activity of yeast frataxin.
Park S, Gakh O, Mooney SM, Isaya G
Journal of Biological Chemistry (2002)
Category: mitochondrial diseases ¤ Added: Oct 15th, 2002 ¤
|Physical evidence that yeast frataxin is an iron storage protein.
Gakh O, Adamec J, Gacy AM, Twesten RD, Owen WG, Isaya G
Category: iron ¤ Added: Jun 12th, 2002 ¤
|Protein import and processing reconstituted with isolated rat liver mitochondria and recombinant mitochondrial processing peptidase.
Cavadini P, Gakh O, Isaya G
Category: methods ¤ Added: Jun 12th, 2002 ¤
|Assembly and iron-binding properties of human frataxin, the protein deficient in Friedreich ataxia.
Cavadini P, O'Neill HA, Benada O, Isaya G
Human Molecular Genetics (2002)
Category: mitochondrial diseases ¤ Added: Mar 12th, 2002 ¤